BMJ Rapidrecs for Transcatheter aortic valve implantation versus surgical aortic valve replacement for severe aortic stenosis in low-intermediate risk patients

Published by Per Olav Vandvik, on behalf of the RapidRecs panel on May 16, 2017

Disclaimer

These recommendations are made according to standards for trustworthy guidelines and targets an international audience with an individual patient perspective. Adaptation to specific countries or contexts should be considered, including the cost-effectiveness of interventions.

Sponsors

The Rapidrecs panel includes clinicians, researchers, methodologists and patient representatives funded by their own institutions, without conflicts of interest and ties with industry. Please see the BMJ RapidRecs publication for details about the RapidRecs panel, their affiliations and declarations of interest. Per O Vandvik, associate professor, Catherine M Otto, professor, Reed A Siemieniuk, methodologist, Rodrigo Bagur, assistant clinical professor, Gordon H Guyatt, distinguished professor,Lyubov Lytvyn, methodologist, Richard Whitlock, associate professor,Trond Vartdal, consultant physician, David Brieger, professor, Bert Aertgeerts, professor, Susanna Price, professor, Farid Foroutan, graduate student, Michael Shapiro, community representative, Ray Mertz, community representative, Frederick A. Spencer, professor

Contact

Abstract

The BMJ-RapidRecs project represents a collaboration between MAGIC and The BMJ. In response to potentially practice-changing evidence a guideline panel creates recommendations and all underlying content in MAGICapp, informed by linked systematic reviews. The BMJ publishes the recommendations and systematic reviews in their journals.

Language

en

PICOS

PICO 1.1

Population
Patients above 85 years with severe symptomatic aortic stenosis, at low or intermediate perioperative risk
Intervention
Transfemoral Transcatheter aortic valve insertion (TAVI)
Comparator
Surgical aortic valve replacement
Outcomes

PICO 1.2

Population
Patients 75-85 years with severe symptomatic aortic stenosis who are at low or intermediate perioperative risk
Intervention
Transfemoral Transcatheter aortic valve insertion (TAVI)
Comparator
Surgical aortic valve replacement (SAVR)
Outcomes

PICO 1.3

Population
Patients 65-75 years with severe symptomatic aortic stenosis who are at low or intermediate perioperative risk
Intervention
Transfemoral Transcatheter aortic valve insertion (TAVI)
Comparator
Surgical aortic valve replacement (SAVR)
Outcomes

PICO 1.4

Population
Patients 65 years and below with severe symptomatic aortic symptomatic stenosis who are at low or intermediate perioperative risk
Intervention
Transfemoral Transcatheter aortic valve insertion (TAVI)
Comparator
Surgical aortic valve replacement (TAVR)
Outcomes

PICO 1.5

Population
Patients with severe symptomatic aortic stenosis who are at low or intermediate perioperative risk who can not undergo transfemoral TAVR
Intervention
Transapical Transcatheter aortic valve insertion (TAVI)
Comparator
Surgical aortic valve replacement (SAVR)
Outcomes