Patent foramen ovale closure, antiplatelet therapy or anticoagulation therapy for management of cryptogenic stroke

Published by Ton Kuijpers, Fred Spencer, Reed Siemieniuk, Gordon Guyatt on Jul 26, 2018

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Abstract

A BMJ-Rapid Recommendation on patent foramen ovale closure, antiplatelet therapy or anticoagulation therapy for management of cryptogenic stroke. This is the 10th BMJ-RapidRec, initiated in response to three recently published large trials in the New England Journal of Medicine (Mas 2017;377(11):1011-1021; Saver 2017;377(11):1022-1032; S√łndergaard 2017;377:1033-42). Roles: Panel Chair: Fred Spencer Methods Editors: Ton Kuijpers Oversight from RapidRecs executive: Reed Siemieniuk, Thomas Agoritsas, Gordon Guyatt, Per Olav Vandvik Systematic Review Lead: Hassan Mir

Language

en

PICOS

PICO 2.1

Population
Patients with cryptogenic stroke ,
Intervention
PFO closure plus antiplatelet therapy ,
Comparator
Antiplatelet therapy ,
Outcomes
,

PICO 2.2

Population
Patients with cryptogenic stroke
Intervention
PFO closure plus antiplatelet therapy
Comparator
Anticoagulation
Outcomes

PICO 2.3

Population
Patients with cryptogenic stroke
Intervention
Anticoagulation
Comparator
Antiplatelet
Outcomes