NFOG guideline: Progesterone for prevention of preterm birth

Published by Jeannet Lauenborg on Jul 2, 2019

Disclaimer

Sponsors

Nordic Federation of Obstetrics and Gynecology (NFOG)

Contact

Abstract

Language

en

PICOS

PICO 3.1

Population
Women with a singleton pregnancy and a history of spontaneous abortion/preterm birth between 16+0 and 37 weeks unless explained by twins, placental abruption, trauma, conization or similar.
Intervention
Progesterone, vaginal (100, 200 and 400 mg), before week 24
Comparator
Placebo/NT
Outcomes

PICO 3.2

Population
Women with a singleton pregnancy and a history of spontaneous abortion/preterm birth between 16+0 and 37 weeks unless explained by twins, placental abruption, trauma, conization or similar.
Intervention
Progesterone, intramuscular, before week 24
Comparator
Placebo/NT
Outcomes

PICO 4.1

Population
Pregnant women with a singleton pregnancy and a short cervix below 25 mm; no uterine malformation and no cerclage.
Intervention
Vaginal progesterone (100, 200 and 400 mg) before week 24
Comparator
Placebo/NT
Outcomes