VTE, Thrombophilia, Antithrombotic Therapy and Pregnancy: A Norwegian adaptation of the 9th ed. of the ACCP Antithrombotic Therapy and Prevention of Thrombosis Evidence-based Clinical Practice Guidelines

Published by Anne Flem Jacobsen on Aug 4, 2015

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This chapter is translated from the Norwegian guideline chapter on thrombosis in pregnancy

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Abstract

Language

en

PICOS

PICO 4.1

Population
Pregnant women on long-term treatment for DVT and pulmonary embolism Acute embolism and thrombosis of unspecified deep veins of lower extremity I82.40, Pulmonary embolism I26, Pregnant woman 255409004, Pulmonary embolism without acute cor pulmonale I26.9, Pulmonary Embolism D011655, Pregnant Women D037841, Pulmonary embolism 59282003, Heparin 5224, Warfarin 11289, Heparin, Low-Molecular-Weight D006495, Warfarin D014859,
Intervention
LMWH Acute embolism and thrombosis of unspecified deep veins of lower extremity I82.40, Pulmonary embolism I26, Pregnant woman 255409004, Pulmonary embolism without acute cor pulmonale I26.9, Pulmonary Embolism D011655, Pregnant Women D037841, Pulmonary embolism 59282003, Heparin 5224, Warfarin 11289, Heparin, Low-Molecular-Weight D006495, Warfarin D014859,
Comparator
Warfarin Acute embolism and thrombosis of unspecified deep veins of lower extremity I82.40, Pulmonary embolism I26, Pregnant woman 255409004, Pulmonary embolism without acute cor pulmonale I26.9, Pulmonary Embolism D011655, Pregnant Women D037841, Pulmonary embolism 59282003, Heparin 5224, Warfarin 11289, Heparin, Low-Molecular-Weight D006495, Warfarin D014859,
Outcomes
Acute embolism and thrombosis of unspecified deep veins of lower extremity I82.40, Pulmonary embolism I26, Pregnant woman 255409004, Pulmonary embolism without acute cor pulmonale I26.9, Pulmonary Embolism D011655, Pregnant Women D037841, Pulmonary embolism 59282003, Heparin 5224, Warfarin 11289, Heparin, Low-Molecular-Weight D006495, Warfarin D014859,

PICO 5.1

Population
Women undergoing assisted reproduction, without OHSS
Intervention
LMWH
Comparator
No treatment
Outcomes

PICO 5.2

Population
Women undergoing assisted reproduction, with OHSS
Intervention
LMWH
Comparator
No treatment
Outcomes

PICO 6.1

Population
Thrombosis with previous thromboembolism: Low risk
Intervention
LMWH
Comparator
No treatment
Outcomes

PICO 6.3

Population
Thrombosis with previous thromboembolism: Moderate-high risk
Intervention
LMWH
Comparator
No treatment
Outcomes

PICO 7.1

Population
Thromboprophylaxis in homozygous Factor V Leiden and prothrombin 20210A mutation
Intervention
LMWH
Comparator
No treatment
Outcomes

PICO 7.2

Population
Thromboprophylaxis in heterozygous factor V Leiden and prothrombin 20210A mutation and family history, Leiden and prothrombin combination
Intervention
LMWH
Comparator
No treatment
Outcomes

PICO 7.3

Population
Thromboprophylaxis in protein C and protein S deficiency with a family history
Intervention
LMWH
Comparator
No treatment
Outcomes

PICO 7.4

Population
Thromboprophylaxis in antithrombin deficiency with or without a family history
Intervention
LMWH
Comparator
No treatment
Outcomes

PICO 7.5

Population
Thromboprophylaxis in Antiphospholipid Syndrome and habitual abortions Anticardiolipin syndrome D68.61, Spontaneous abortion O03, Habitual aborter NOS 199090000, Antiphospholipid syndrome 26843008, Heparin B01A B01, ASA B01A C06, Acetyl salicylate 91101, Heparin 5224, Antibodies, Antiphospholipid D017152, Antibodies, Anticardiolipin D017153, Abortion, Habitual D000026, Heparin D006493, Aspirin D001241,
Intervention
UFH plus ASA Anticardiolipin syndrome D68.61, Spontaneous abortion O03, Habitual aborter NOS 199090000, Antiphospholipid syndrome 26843008, Heparin B01A B01, ASA B01A C06, Acetyl salicylate 91101, Heparin 5224, Antibodies, Antiphospholipid D017152, Antibodies, Anticardiolipin D017153, Abortion, Habitual D000026, Heparin D006493, Aspirin D001241,
Comparator
ASA Anticardiolipin syndrome D68.61, Spontaneous abortion O03, Habitual aborter NOS 199090000, Antiphospholipid syndrome 26843008, Heparin B01A B01, ASA B01A C06, Acetyl salicylate 91101, Heparin 5224, Antibodies, Antiphospholipid D017152, Antibodies, Anticardiolipin D017153, Abortion, Habitual D000026, Heparin D006493, Aspirin D001241,
Outcomes
Anticardiolipin syndrome D68.61, Spontaneous abortion O03, Habitual aborter NOS 199090000, Antiphospholipid syndrome 26843008, Heparin B01A B01, ASA B01A C06, Acetyl salicylate 91101, Heparin 5224, Antibodies, Antiphospholipid D017152, Antibodies, Anticardiolipin D017153, Abortion, Habitual D000026, Heparin D006493, Aspirin D001241,

PICO 8.1

Population
Cesarean section in pregnant women at low risk of VTE
Intervention
LMWH
Comparator
No treatment
Outcomes

PICO 8.2

Population
Cesarean section in pregnant women at moderate risk of VTE
Intervention
LMWH
Comparator
No treatment
Outcomes

PICO 8.3

Population
Cesarean section in pregnant women at high risk of VTE
Intervention
LMWH
Comparator
No treatment
Outcomes

PICO 10.1

Population
Prophylaxis of habitual abortion without known thrombophilia
Intervention
LMWH + ASA
Comparator
No treatment
Outcomes

PICO 10.2

Population
Prophylaxis of habitual abortion without known thrombophilia
Intervention
ASA
Comparator
No treatment
Outcomes

PICO 10.3

Population
Prophylaxis of antiphospholipid syndrome and habitual abortions Anticardiolipin syndrome D68.61, Spontaneous abortion O03, Habitual aborter NOS 199090000, Antiphospholipid syndrome 26843008, Acetylsalisylate B01A C06, Heparin B01A B01, Aspirin 1191, Heparin 5224, Heparin D006493, Aspirin D001241, Antiphospholipid Syndrome D016736, Abortion, Habitual D000026,
Intervention
UFH plus ASA Anticardiolipin syndrome D68.61, Spontaneous abortion O03, Habitual aborter NOS 199090000, Antiphospholipid syndrome 26843008, Acetylsalisylate B01A C06, Heparin B01A B01, Aspirin 1191, Heparin 5224, Heparin D006493, Aspirin D001241, Antiphospholipid Syndrome D016736, Abortion, Habitual D000026,
Comparator
ASA Anticardiolipin syndrome D68.61, Spontaneous abortion O03, Habitual aborter NOS 199090000, Antiphospholipid syndrome 26843008, Acetylsalisylate B01A C06, Heparin B01A B01, Aspirin 1191, Heparin 5224, Heparin D006493, Aspirin D001241, Antiphospholipid Syndrome D016736, Abortion, Habitual D000026,
Outcomes
Anticardiolipin syndrome D68.61, Spontaneous abortion O03, Habitual aborter NOS 199090000, Antiphospholipid syndrome 26843008, Acetylsalisylate B01A C06, Heparin B01A B01, Aspirin 1191, Heparin 5224, Heparin D006493, Aspirin D001241, Antiphospholipid Syndrome D016736, Abortion, Habitual D000026,

PICO 10.4

Population
Prevention of preeclampsia in pregnant women without known thrombophilia
Intervention
ASA
Comparator
No treatment
Outcomes